From strain measurements to assessing El Niño events

Figure 11 from RSOS 201086One of the exciting aspects of leading a university research group is that you can never be quite sure where the research is going next.  We published a nice example of this unpredictability last week in Royal Society Open Science in a paper called ‘Transformation of measurement uncertainties into low-dimensional feature space‘ [1].  While the title is an accurate description of the contents, it does not give much away and certainly does not reveal that we proposed a new method for assessing the occurrence of El Niño events.  For some time we have been working with massive datasets of measurements from arrays of sensors and representing them by fitting polynomials in a process known as image decomposition [see ‘Recognising strain‘ on October 28th, 2015]. The relatively small number of coefficients from these polynomials can be collated into a feature vector which facilitates comparison with other datasets [see for example, ‘Out of the valley of death into a hype cycle‘ on February 24th, 2021].  Our recent paper provides a solution to the issue of representing the measurement uncertainty in the same space as the feature vector which is roughly what we set out to do.  We demonstrated our new method for representing the measurement uncertainty by calibrating and validating a computational model of a simple beam in bending using data from an earlier study in a EU-funded project called VANESSA [2] — so no surprises there.  However, then my co-author and PhD student, Antonis Alexiadis went looking for other interesting datasets with which to demonstrate the new method.  He found a set of spatially-varying uncertainties associated with a metamodel of soil moisture in a river basin in China [3] and global oceanographic temperature fields collected monthly over 11 years from 2002 to 2012 [4].  We used the latter set of data to develop a new technique for assessing the occurrence of El-Niño events in the Pacific Ocean.  Our technique is based on global ocean dynamics rather than on the small region in the Pacific Ocean which is usually used and has the added advantages of providing a confidence level on the assessment as well as enabling straightforward comparisons of predictions and measurements.  The comparison of predictions and measurements is a recurring theme in our current research but I did not expect it to lead into ocean dynamics.

Image is Figure 11 from [1] showing convex hulls fitted to the cloud of points representing the uncertainty intervals for the ocean temperature measurements for each month in 2002 using only the three most significant principal components . The lack of overlap between hulls can be interpreted as implying a significant difference in the temperature between months.

References:

[1] Alexiadis, A. and Ferson, S. and  Patterson, E.A., , 2021. Transformation of measurement uncertainties into low-dimensional feature vector space. Royal Society Open Science, 8(3): 201086.

[2] Lampeas G, Pasialis V, Lin X, Patterson EA. 2015.  On the validation of solid mechanics models using optical measurements and data decomposition. Simulation Modelling Practice and Theory 52, 92-107.

[3] Kang J, Jin R, Li X, Zhang Y. 2017, Block Kriging with measurement errors: a case study of the spatial prediction of soil moisture in the middle reaches of Heihe River Basin. IEEE Geoscience and Remote Sensing Letters, 14, 87-91.

[4] Gaillard F, Reynaud T, Thierry V, Kolodziejczyk N, von Schuckmann K. 2016. In situ-based reanalysis of the global ocean temperature and salinity with ISAS: variability of the heat content and steric height. J. Climate. 29, 1305-1323.

Seeing things with nanoparticles

Photograph showing optical microscope and ancilliary equipment set up on an optical benchLast week brought excitement and disappointment in approximately equal measures for my research on tracking nanoparticles [see ‘Slow moving nanoparticles‘ on December 13th, 2017 and ‘Going against the flow‘ on February 3rd, 2021]. The disappointment was that our grant proposal on ‘Optical tracking of virus-cell interaction’ was not ranked highly enough to receive funding from Engineering and Physical Sciences Research Council. Rejection is an occupational hazard for academics seeking to win grants and you learn to accept it, learn from the constructive criticism and look for ways of reworking the ideas into a new proposal. If you don’t compete then you can’t win. The excitement was that we have moved our apparatus for tracking nanoparticles into a new laboratory, which has been set up for it, so that we can start work on a pilot study looking at the ‘Interaction of bacteria and viruses with cellular and hard surfaces’.  We are also advertising for a PhD student to start in September 2021 to work on ‘Developing pre-clinical models to optimise nanoparticle based drug delivery for the treatment of diabetic retinopathy‘.  This is an exciting development because it represents our first step from fundamental research on tracking nanoparticles in biological media towards clinical applications of the technology. Diabetic retinopathy is an age-related condition that threatens your sight and currently is managed by delivery of drugs to the inside of the eye which requires frequent visits to a clinic for injections into the vitreous fluid of the eye.  There is potential to use nanoparticles to deliver drugs more efficiently and to support these developments we plan that the PhD student will use our real-time, non-invasive, label-free tracking technology to quantify nanoparticle motion through the vitreous fluid and the interaction of nanoparticles with the cells of the retina.

 

On the impact of writing on well-being

Poster showing five ways to well-being: connect, be active, take notice, keep learning, giveLast week, the continuation until at least the end of March of the lockdown, which has been in place in England since the start of the year, was announced. Many people are feeling jaded and worn out by the constraints and hardships imposed by the lockdown and are struggling to maintain their well-being and mental health. While others are trying to cope with the direct impact of the coronavirus on themselves and their family and friends. I have written before about the power of writing to transport me away from the pressures of everyday life [see ‘Feeling extraordinary at ease‘ on January 8th, 2020] and to help me order my thoughts [see ‘Thinking more clearly by writing weekly‘ on May 2nd, 2018].  These posts were inspired by reading books by Natalia Ginzburg and Sylvain Tesson.  I have just finished reading ‘A Fly Girl’s Guide to University‘ edited by Odelia Younge in which Suhaiymah Manzoor-Khan writes about ‘times when my mental health was bad…writing became a solace and a friend’.  In the context of institutional pressures, racism and exclusion, she describes writing about her feelings to help her to feel and listening to her own voice when nobody else would.  I was reading the book to gain an appreciation of the experiences of woman of colour in a university; however, I think Manzoor-Khan’s words are relevant to everyone, especially when we are locked away and can only meet with much of our support networks via our computers and phones.  Tim Hayward, in the FT in January 2021, wrote a deeply moving and insightful account of his experience of fighting coronavirus, including ten days on life support, and concludes by reflecting on how writing the article helped him handle the trauma.  Of course, you don’t have to write for a newspaper, a book or a blog; although writing for an audience does focus your mind, you can write for yourself or friend and in doing so you can keep learning, take notice of your surroundings, and connect with people which will hit three out of five of the ways to well-being.

Sources:

Lola Olufemi, Odelia Younge, Waithera Sebatindira & Suhaiymah Manzoor-Khan, A Fly Girl’s Guide to University, Verve Poetry Press, Birmingham, 2019

Tim Hayward, Covid and me: 10 days on life support, FT Magazine, January 22nd, 2021.

Out of the valley of death into a hype cycle?

Fig 5 from Middleton et al with full captionThe capability to identify damage and track its propagation in structures is important in ensuring the safe operation of a wide variety of engineering infrastructure, including aircraft structures. A few years ago, I wrote about research my group was performing, in the INSTRUCTIVE project [see ‘INSTRUCTIVE final reckoning‘ on January 9th, 2019] with Airbus and Strain Solutions Limited, to deliver a new tool for monitoring the development of damage using thermoelastic stress analysis (TSA) [see ‘Counting photons to measure stress‘ on November 18th, 2015].  We collected images using a TSA system while a structural component was subject to cycles of load that caused damage to initiate and propagate during a fatigue test. The series of images were analysed using a technique based on optical flow to identify apparent movement between the images which was taken as indication of the development of damage [1]. We demonstrated that our technique could indicate the presence of a crack less than a millimetre in length and even identify cracks initiating under the heads of bolts using experiments performed in our laboratory [see ‘INSTRUCTIVE update‘ on October 4th, 2017].  However, this technique was susceptible to errors in the images when we tried to use low-cost sensors and to changes in the images caused by flight cycle loading with varying amplitude and frequency of loads.  Essentially, the optical flow approach could be fooled into identifying damage propagation when a sensor delivered a noisy image or the shape of the load cycle was changed.  We have now overcome this short-coming by replacing the optical flow approach with the orthogonal decomposition technique [see ‘Recognising strain‘ on October 28th, 2015] that we developed for comparing data fields from measurements and predictions in validation processes [see ‘Million to one‘ on November 21st, 2018] .  Each image is decomposed to a feature vector and differences between the feature vectors are indicative of damage development (see schematic in thumbnail from [2]).  The new technique, which we have named the differential feature vector method, is sufficiently robust that we have been able to use a sensor costing 1% of the price of a typical TSA system to identify and track cracks during cyclic loading.  The underpinning research was published in December 2020 by the Royal Society [2] and the technique is being implemented in full-scale ground-tests on aircraft structures as part of the DIMES project.  Once again, a piece of technology is emerging from the valley of death [see ‘Slowly crossing the valley of death‘ on January 27th, 2021] and, without wishing to initiate the hype cycle [see ‘Hype cycle‘ on September 23rd, 2015], I hope it will transform the use of thermal imaging for condition monitoring.

Logos of Clean Sky 2 and EUThe INSTRUCTIVE and DIMES projects have received funding from the Clean Sky 2 Joint Undertaking under the European Union’s Horizon 2020 research and innovation programme under grant agreements No. 685777 and No. 820951 respectively.

The opinions expressed in this blog post reflect only the author’s view and the Clean Sky 2 Joint Undertaking is not responsible for any use that may be made of the information it contains.

References

[1] Middleton CA, Gaio A, Greene RJ & Patterson EA, Towards automated tracking of initiation and propagation of cracks in Aluminium alloy coupons using thermoelastic stress analysis, J. Non-destructive Testing, 38:18, 2019.

[2] Middleton CA, Weihrauch M, Christian WJR, Greene RJ & Patterson EA, Detection and tracking of cracks based on thermoelastic stress analysis, R. Soc. Open Sci. 7:200823, 2020.